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阿托伐他汀治疗脑梗死中运动捕捉与运动评估量表和Barthel指数疗效评价的比较

Comparison of Motion Capture and Motor Assessment in Evaluatint of Effect on Treatment of Patients with Cerebral Infarction with Atorvastatin

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【作者】 林永忠孙长凯宋桂荣胡增春尹琳姜长斌包礼平

【Author】 LIN Yong-Zhong, SUN Cang-Kai 1, SONG Gui-Rong 2, HUZeng-Chun, YIN Lin, JIANG Chang-Bin, BAO Li-Ping Department of Neurology, The Second AffiliatedHospital; 1 Institution of Brain Disease; 2 Department of Statistics,Dalian Medical University, Dalian 116027,China

【机构】 大连医科大学附属第二医院神经内科大连医科大学附属第二医院脑疾病研究所大连医科大学附属第二医院统计学教研室大连医科大学附属第二医院神经内科 116027116027

【摘要】 目的:运动捕捉(MoCA)分析脑梗死后肢体运动状态,探讨阿托伐他汀(立普妥)对脑梗死预后影响。方法:43例脑梗死患者分对照组和阿托伐他汀组。在急性期和3个月应用运动评估量表(MAS)及Barhel指数(BI)评分;MoCA分析肢体运动状态。结果:两组3个月时与急性期比较MAS、BI均增加(P<0.01),但组间无统计学差异;MoCA分析患侧与健侧肢体抬高高度差值的均数均减小,阿托伐他汀组明显,有统计学差异(P<0.05),但组间无统计学差异。结论:长期应用阿托伐他汀对脑梗死预后改善不明显,需进一步研究;MoCA是一种评估运动障碍程度的较好方法。

【Abstract】 Aim: To analyze motion state of limbs after cerebral infarction with motion capture analysis system(MoCA) and discuss the effect of applying statins-related drug in acute stage on long-term prognosis of cerebralinfarction. Methods: 43 cases with acute cerebral infarction were divided into control group and atorvastatin groupby using random control method. The neurologic deficit scale with motor assessment scale and Barthel Index scoringmethod were performed in acute stage and 3 months after stroke, respectively. Motion function state was analyzedwith MoCA. Results: There was a significant difference (P<0.01) between acute stage with 3 months afterepisode of cerebral infarction in MAS and BI group, however, there was no difference between the two groups. MoCAcould reflect objectively motion orbit of limbs joint and find the difference (uninjured side-injured side) of averageof height bilateral limbs raise between acute stage and 3 months after stroke. Conclusion: Application of atorvastatinin long-term was not of apparent effect on prognosis of cerebral infarction, and the therapeutic effect of atorvastatinon acute cerebral infarction needed to be further studied. MoCA was a better approach to evaluate the degree ofmotion disorder.

【关键词】 量表运动捕捉脑梗死他汀类
【Key words】 scalemotion capturecerebral infarctionstatins
【基金】 国家自然科学项目基金(No.30470682)
  • 【文献出处】 中国临床神经科学 ,Chinese Journal of Clinical Neurosciences , 编辑部邮箱 ,2006年02期
  • 【分类号】R743.33
  • 【被引频次】2
  • 【下载频次】141
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