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神经妥乐平治疗老年带状疱疹后神经痛的疗效观察

Therapeutic effect observation of Neurotropin in the treatment of senile postherpetic neuralgia

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【作者】 梁临平李美晔张宪军

【Author】 LIANG Lin-ping,LI Mei-ye,ZHANG Xian-jun. Department of Dermatology, Qilu Hospital, Shandong University, Jinan 250012, China

【机构】 山东大学齐鲁医院皮肤科山东大学齐鲁医院神经内科山东大学齐鲁医院皮肤科 250012研究生在读

【摘要】 目的观察神经妥乐平治疗老年带状疱疹后神经痛(PHN)的疗效。方法将58例老年PHN患者随机分为神经妥乐平组和卡马西平组,应用视觉模糊评分法(VAS)评价两组治疗后疼痛的改善情况并观察药物不良反应。结果治疗第2周、4周、6周后神经妥乐平组VAS较治疗前明显下降(均P<0.01),总有效率为80%,明显优于卡马西平组(46.4%)(P<0.05),两组患者均未出现明显不良反应。结论神经妥乐平治疗老年PHN的疗效优于卡马西平。

【Abstract】 Objective To discuss the efficacy of Neurotropin in the treatment of senile postherpes neuralgia.Methods 58 senile patients with postherpes neuralgia were randomly divided into Neurotropin group and Carbamazepine group. Before and after treatment, symptoms and signs of neuropathy including pain and numbness were evaluated by vision ambiguity scales(VAS). The side effects of drugs were also observed.Results 2,4,6 weeks of post-therapy,the VAS of Neurotropin group was decreased obviously than that of pretherapy (all P<0.01). The improvement rate of pain in Neurotropin group was significantly better than that of the Carbamazepine group (80% vs 46.4%, P<0.05). There was no obvious adverse effect in two groups.Conclusion Neurotropin is effective in the treatment of senile postherpes neuralgia, and is better than Carbamazepine.

【关键词】 神经妥乐平卡马西平神经痛
【Key words】 NeurotropinCarbamazepineneuralgia
  • 【文献出处】 临床神经病学杂志 ,Journal of Clinical Neurology , 编辑部邮箱 ,2006年03期
  • 【分类号】R752.12
  • 【被引频次】17
  • 【下载频次】160
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