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老年期抑郁症患者瞬目反射的研究
Study of blink reflex in aged depression
【摘要】 目的:探讨老年期抑郁症与瞬目反射(BR)的关系。方法:对34例老年期抑郁症患者及30名正常老年人进行BR检测,并对其中19例患者于治疗后进行复测。结果:患者组在左侧R2、R2′潜伏期以及右侧R2潜伏期指标显著高于对照组(P<0.01);患者组R1与R2、R1与R2′波潜伏期差值明显大于对照组。左侧R1与R2、R1与R2′,右侧R1与R2波潜伏期差值与对照组比较差异显著。19例患者治疗前后各项BR指标差异均无显著性。治疗前后HAMD变化与BR各项指标变化无显著相关。结论:老年期抑郁症患者存在BR异常,提示老年期抑郁症患者可能存在脑干功能障碍。
【Abstract】 Objective:To evaluate the relationship between eldly depression and blink reflex (BR). Method:34 aged patients with depression and 30 healthy controls were measured with BR, among them,19 patients were redetected after treatments. Results:The index of R2 and R2′ latency in the left and R2 latency in the right were significantly higher in patient group than in control group (P<0.01).The differences between R1 and R2,R1 and R2′ latency in patient group were longer than those in control group.The differences between R1 and R2、R1 and R2′ in the left and R1 and R2 in the right were significantly different between two groups.There was no significant difference in BR in 19 treated patients between pre-treatment and after-treatment.There was no significant correlation between the reduction rate of HAMD and index of BR before and after treatment. Conclusion:There is abnormity of blink reflex in aged depression,which indicates that brain stem might has functionary disorder in aged depression.
- 【文献出处】 临床精神医学杂志 ,Journal of Clinical Psychiatry , 编辑部邮箱 ,2006年04期
- 【分类号】R749.4
- 【被引频次】5
- 【下载频次】43