【摘要】 采用水蒸气蒸馏和超临界CO2提取与气-质联用技术对厚朴药材中的化学成分进行了研究。结果表明超临界CO2提取的厚朴化学成分比用水蒸气蒸馏的化学成分少,而厚朴酚与和厚朴酚的相对含量却较高。超临界CO2提取的主要成分为新木脂素类化合物如厚朴酚与和厚朴酚;而水蒸气蒸馏的主要成分为倍半萜和氧化倍半萜类化合物如α-桉醇、十氢-α,,α4 a-三甲基-8-亚甲基-2-萘甲醇。水蒸气蒸馏和超临界CO2提取物中均含有咕吧烯、石竹烯、桉叶二烯、α-依兰油烯、1,2,3,5,6,8 a-六氢-4,7-二甲基-1-异丙基萘、1,2,3,4,4A,5,6,8 a-八氢-8-四甲基-2-羟甲基萘。除文献已报道的化合物外,一些化合物如桉叶二烯、1,2,3,5,6,8 a-六氢-4,7-二甲基-1-异丙基萘、α-白檀油烯醇、4-亚甲基-1-甲基-2-(2-甲基-1-丙烯)-1-乙烯基-环庚烷、4,5,6,6 a-四氢-2(1H)-并环戊二烯酮、十氢-α,,α4 a-三甲基-8-亚甲基-2-萘甲醇,β-人参烯和苍术醇也被鉴定出来。更多还原

【Abstract】 Chemical constituents of extracts from Magnolia officinalis Rehd.et Wils.bark were studied through steam distillation,supercritical CO₂extraction and GC-MS technology.The study revealed that chemical components by supercritical CO₂extraction possessed less chemical constituents but higher relative contents of magnolol and honokiol than those by steam distillation.Components from M.officinalis by supercritical CO₂ extraction mainly contained neolignans such as magnolol and honokiol.However,components by steam distillation were mainly sesquiterpenes and oxygenated sesquiterpenes such as α-eudesmol,decahydro-α,α,4a-trimethyl-8-methylene-2-naphthalene-methanol.Substances by steam distillation and supercritical CO₂ extraction have the（common） components such as copanen,caryophyllene,eudesma-4（14）,11-diene,α-muurolene,1,2,3,5,6,8a-hexahydro-4,7-dimethyl-1-（1-methylethyl）-naphthalene and 1,2,3,4,4A,5,6,8a-octahydro-8-tetramethyl-2-naphthalene-methanol.Except those compounds that have been reported,some compounds such as eudesma4（14）,11-diene,1,2,3,5,6,8a-hexahydro-4,7-dimethyl-1-（1-methylethyl）-naphthalene,α-santalol,4-methylene-1-methyl-2-（2-methyl-1-propen-1-yl）-1-vinyl-cycloheptane,4,5,6,6a-tetrahydro-2（1H）-pentalenone,decahydro-α,α,4a-trimethyl-8-methylene-2-naphthalenemethanol, β-panasinsene and hinesol were identified.更多还原