【摘要】 考察了一种实验室自制的魔芋葡甘聚糖季铵盐衍生物(KGM-g-DMAE-BC)的合成以及抗菌性能。正交试验优选出的最佳合成条件为:反应温度70℃,单体质量比(mKGM∶mDMAE-BC)1∶5,引发剂用量0.7 mmol/L,反应时间3 h。悬菌定量实验结果表明:KGM-g-DMAE-BC(接枝率为38.5%)对大肠杆菌、金黄色葡萄球菌及白色念珠菌有较强的杀菌作用,在振荡作用15 m in后,平均灭杀率分别为99.99%、94.26%和99.99%。更多还原

【Abstract】 The grafted polymer of konjac glucomannan（KGM） with methacryloxylethyl benzyl dimethyl ammonium chloride（KGM-g-DMAE-BC） had been prepared and its antibacterial activity was investigated.The optimum technological conditions were: reaction time 3 h,temperature 70 ℃,m_KGM ∶m_DMAE-BC 1 ∶5 and dosage of initiator 0.7 mmol/L. The KGM-g-DMAE-BC was confirmed by Fourier-transform infrared spectroscopy （FT-IR）.Antibacterial activities of KGM-g-DMAE-BC（against） a variety of microorganisms had been examined by quantitative suspension test using shaking flask.The obtained polymer was inhibitive（against） gram-negative bacteria（Escherichia coli）,gram-positive bacteria（Staphylococcus aureus） and fungus（Candida（albicans））,at becteriostatic rates of 99.99 %,94.26 %,99.99%,respectively.更多还原