【摘要】 探讨乙肝患者血清中补体C3(C3)、转铁蛋白(Tf)、α1-抗胰蛋白酶(α1-AT)含量的变化与肝脏损伤之间的关系。将患者分为急肝组(AH)、慢肝组(CH)、肝硬化组(LC)和肝癌组(HCC)。用速率散射比浊法检测。其结果为:C3各肝病组的含量与对照组相比都下降(P<0.05);AH组、CH组和HCC组均高于LC组,差异有显著性(P<0.01),Tf:各肝病组的含量与对照组相比都下降,差异有显著性(P<0.01)。AH组和CH组分别高于LC组、HCC组,差异有显著性。(P<0.01)α1-AT:AH组和HCC组高于对照组(P<0.01);HCC组高于CH组(P<0.05),差异有显著性。检测乙型肝炎患者血清中的C3、Tf、α1-AT含量,对监测患者肝脏损伤的程度和肝炎的进程有一定的参考意义。更多还原

【Abstract】 To study the relation between the change of concentration of complement 3（C₃）、transferrin（Tf） and α₁-antitrypsin（α₁-AT） in sera of patients with hepatitis B and the damage of liver.healthy adults are used as controls.Patients with hepatitis B are divided into four groups: Actue hepatitis（aH）、chronic hepatitis（CH）、liver cirrhosis（LC） and liver cancer（HCC）.Detect the concentration by ratenephelometer.Results C₃: All groups of hepatitis B are lower than the control group.AH、CH and HCC are higher than LC（P<0.01）,The differences are significant.Tf: All the groups of hepatitis B are lower than the control group,the differences are significant（P<0.01）.AH and CH are higher than LC or HCC,The differences are significant.（P<0.01） α₁-AT: AH and HCC are higher than control（P<0.01）;HCC is higher than CH.（P<0.05）;The differences are significant.There is a significance to observe the degree of the damage of liver and the course of hepatitis detecting the concentration of C₃、Tf and α₁-AT in sera of patients with hepatitis B.更多还原