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高压氧治疗对原发性脑干损伤患者血糖的影响和疗效分析
Effect of hyperbaric oxygen on plasma glucose levels and prognosis in patients with primary brain stem injury
【摘要】 目的:探讨高压氧(HBO)治疗与原发性脑干损伤(PBS I)患者血糖和预后的关系。方法:64例PBS I患者分为HBO治疗组(HBO组)和常规治疗组(对照组)。测定两组患者治疗10d前后血糖浓度。按GO S标准判断疗效。结果:治疗后两组患者血糖均显著下降(P<0.01),且HBO组下降较对照组明显(P<0.05)。HBO组患者平均昏迷时间39 d,死亡8例,植物生存1例。对照组平均昏迷时间52 d,死亡15例,植物生存2例。HBO组疗效显著高于对照组(χ2=4.14,P<0.05)。结论:PBS I患者血糖显著升高,HBO能够降低PBS I患者升高的血糖,对PBS I的治疗有效。
【Abstract】 Objective:To explore the relationship between hyperbaric oxygen treatment,plasma glucose level and prognosis in the patients with primary brain stem injury(PBSI).Methods:Sixty-four patients with PBSI were divided into hyperbaric oxygen treated group(HBO group) and routine treated group(control group).In all patients,the plasma glucose level was measured before and after 10-day treatment.The neurological prognosis was evaluated with glasgow outcome scale(GOS).Results:After 10-day treatment,the plasma glucose levels of two group were significantly lower than those before treatment respectively(P<0.01),and the plasma glucose value in HBO group was significantly decreased compared with control group(P<0.05).In HBO group,the average time of stupor was 39 days,8 cases died and 1 case alive as a persistent vegetative state(PVS),while in control group,the average time of stupor was 52 days,15 cases died and 2 cases alive as a PVS.The treatment efficacy in HBO group was significantly higher than that in control group(χ~2=4.14,P<0.05).Conclusion:The Patients with PBSI frequently develop hyperglycemia.Hyperbaric oxygen treatment may decrease plasma glucose in patients with PBSI and is an effective approach for patients with PBSI.
【Key words】 hyperbaric oxygen; brain stem; brain injury; plasma glucose; prognosis;
- 【文献出处】 黑龙江医药科学 ,Heilongjiang Medicine and Pharmacy , 编辑部邮箱 ,2006年06期
- 【分类号】R459.6;R651
- 【下载频次】12