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四种植骨材料对血小板粘附的实验研究

An Experimental Research of Platelet-Rich Plasma(PRP) Adhesion to Four Bone Substitutes

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【作者】 李建斌; 王艺; 马建伟;

【Author】 LI Jianbin,WANG Yi,MA Jianwei Dept. of Dentistry, Shanghai Dongfang Hospital affiliated to Tongji University, SHANGHAI, CHINA

【机构】 同济大学附属上海东方医院口腔种植修复中心; 同济大学附属上海东方医院口腔种植修复中心;

【摘要】 目的:检测四种口腔种植临床常用植骨材料对血小板的粘附能力。方法:分别将Bio-oss、PepGen-15、Algipore和Perioglas加入人PRP,在37℃水浴中分别放置10min、20min和30min,计算血小板粘附数目及四种材料和PRP混合最佳时间,并计算单位重量材料粘附血小板数;同时用环境扫描电镜验证四种材料粘附血小板的情况。结果:PepGen-15粘附血小板的性能最好;Perioglas、Bio-oss和Algipore三者之间未显示统计学差异。结论:不同植骨材料粘附血小板的能力不同,临床应根据其粘附特性决定患者取血量和最佳混合时间。

【Abstract】 Object: To detect and research the capability of PRP adhesion to the four ordinary bone-substitutes in dental implant clinic. Method: Four bone-substitutes ( Bio-oss, PepGen-15, Algipore and Perioglas) were chosen in this experiment. Every material was placed into the water(37℃) with PRP for 10min?20min and 30min respectively, to detect the capability of PRP adhesion to the four bone-substitutes with environmental scanning electron microscopy(ESEM); to explore the best time when the material and PRP were mixed; and to calculate the number of PRP adhesion to per gram bone-substitute. Result: PepGen-15 has the best capability of adhesion to PRP among the four bone-substitutes, the others have no statistical difference. Conclusion: The capabilities of PRP adhesion to the four bone-substitutes are different. In the clinical use, we should decide the quantity of patients’ blood needed and the mixed time according to the different materials.

【基金】 上海市科委启明星培养计划(03QD14056)
  • 【文献出处】 中国口腔种植学杂志 ,Chinese Journal of Oral Implantology , 编辑部邮箱 ,2006年03期
  • 【分类号】R318.08;R783.1
  • 【被引频次】1
  • 【下载频次】190
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