【摘要】 目的监测恶性肿瘤化疗患者合并败血症病原菌分布及常见病原菌耐药情况,指导抗菌药物的应用。方法对我院112例肿瘤化疗患者合并败血症进行回顾性分析。用K-B法进行药敏实验,按NCCLS标准判断细菌耐药性,并对革兰氏阳性球菌和革兰氏阴性杆菌排位前三位的病原菌耐药性进行分析。结果112株病原菌中,以凝固酶阴性葡萄球菌、大肠埃希氏菌、金黄色葡萄球菌、肠球菌、不动杆菌、克雷伯菌为主,病原菌对常用抗菌药物耐药率较高。结论临床需掌握恶性肿瘤化疗患者合并败血症病原菌分布及其对常见抗菌药物的耐药特点,合理应用抗菌药物提高疗效。更多还原

【Abstract】 Objective To study the pathogens and drug sensitivity test of Septicemia patients with malignancy in chemotherapy to direct the uses of antibiotics.Methods The clinical data of 112 cases of Septicemia with malignancy in chemotherapy were analyzed respectively.All of the isolates were tested by Kirby-Bauer susceptibility,and the antibiotic resistance was judged according to NCCLS standard.Results Coagulase-negative S taphylococcus,E.coil,S.aureus,Enterococcus,Acinetobacter,were the main pathogens,Bacteria were highly resistant to ordinary antibacterials.Conclusion Much attention should be paid to drug resistance detection in the treatment of malignancy septicemia.Choosing sensitive antibiotics based on the drug sensitivity tests may decrease the occurrence of drug resistant bacteria and increase the clinical curative effects.更多还原