【摘要】 建立了高效液相色谱-质谱法同时测定生鲜牛奶中杀线威、涕灭威残留量的方法。样品用乙酸乙酯提取,C18固相萃取柱纯化、富集,采用电喷雾正离子模式离子化。在质谱图中,[M+Na]+强度最大,定量测定使用多离子监测模式m/z:242→72,213→116。杀线威、涕灭威的检测限分别为0.4 ng、0.1 ng,方法的平均回收率:杀线威为92.5%~95.6%、涕灭威为91.6%~93.4%。方法的灵敏度高,选择性好。用于实际样品的分析,获得满意的效果。更多还原

【Abstract】 A liquid chromatographic method,with electrospray ionization tandem mass spectrometry（LC-ESI-MS/MS）,has been developed for simultaneously determining Oxamyl and Aldicarb in milk.The sample was extracted by ethyl acetate,and purified by C₁₈,The most prominent ion in ESI-MS spectra were⁺,The mass spectrometer was operated in the positive mode using multiple reaction monitoring m/z:242→72,213→116 for qualitative and quantitative analysis of these compounds at the same time.The limits of detection（LOD） of Oxamyl and Aldicarb were 0.4ng and 0.1ng;and average recoveries ranged from 92.5%⁹5.6% to Oxamyl and 91.6%⁹3.4% to Aldicarb.The advantages of the method are sensitive and high selection.The method is applied to detect the residues in real sample with satisfactory results.更多还原