【摘要】 目的:探讨精神分裂症与遗传学的关系.方法:随机抽取门诊和住院确诊为精神分裂症的100份病例,将其一级亲属的患病状况进行登记.以性别、年龄、人数与患者相同的健康人群一级亲属作为对照,计算精神分裂症的遗传度.结果:17~40岁发病者占73%,因此可将此年龄段视为精神分裂症患病的危险年龄,精神分裂症的遗传度为70.85%.结论:精神分裂症的易感性和家族聚集性主要是由遗传因素决定的,但环境因素对精神分裂症的发病也有一定的影响,属于多基因遗传.更多还原

【Abstract】 Objective:To study the relationship between schizophrenia and genetics.Methods:100 cases with schizophrenia by clinic and hospital diagnosis were collected randomly.Register the patient hood of their first-degree relatives and make the ones of healthy population which had the same gender,age and numbers in control,then calculate the heritability of schizophrenia.Results:Patients aged 17~40 is 73%,so this age group was regarded as risk stage of schizophrenic patients,the heritability of schizophrenia is 70.85%.Conclusion:Schizophrenic susceptibility and family accumulation were mainly determined by genetic factors,however environmental factors also had some influence on the cause of schizophrenia.The schizophrenia is polygenic inheritance.更多还原