节点文献
用于生化分析的聚二甲基硅氧烷微混合器
Polymethylsiloxane micromixer in biochemical analyse
【摘要】 对一种电磁式微腔体混合器的设计、制作及实验进行了研究。从提高其混合性能出发,对混合器进行了动力学分析,得出了适于快速混合的振动模式。结果表明,混合效果是由驱动频率及振幅共同决定的。利用模压工艺制作出适于光学探测的聚二甲基硅氧烷(PDMS) 混合器。利用DE-LIGA工艺制作出的平面线圈,具有结构紧凑,不易脱落等优点。设计的微混合芯片由PDMS混合器、永磁体、光学透镜、平面线圈、微型光谱仪等混合集成,并对振动膜厚度为50 μm的φ6 mm混合器进行定量检测,当混合量为150μL时,动态混合能在5 s内完成。
【Abstract】 The design, fabrication and evaluation of a new microchamber electromagnetic mixer were described. The dynamic analysis was applied to the mixer in order to improve its mixing performance. The computational results proved that the mixing efficiency is dependent on both frequency and amplitude of membrane vibration. The polymethylsiloxane (PDMS) mixers used in optical evaluation were fabricated by mold pressing. The planar coils manufactured by DE-LIGA are characterized by compactness and good adhesion. The hybrid integrated mixer chip consists of PDMS mixer, magnet, optical lens, planar coils and mini spectrometer, et al. Its mixing experiments show that the φ6 mm mixer with membrane thickness 50μm achieves good mixing of volume 150 μL in 5 s.
【Key words】 micromixer; finite element method (FEM); polymethylsiloxane (PDMS); mixing evaluation;
- 【文献出处】 吉林大学学报(工学版) ,Journal of Jilin University(Engineering and Technology Edition) , 编辑部邮箱 ,2006年S1期
- 【分类号】TH776.2
- 【被引频次】2
- 【下载频次】111