【摘要】 目的探讨131I治疗G raves’病后突眼的转归与TRAb及TGA、TMA的关系,为临床治疗G raves’病后突眼提供理论参考。方法选择伴有突眼的G raves’病患者78例进行131I治疗,在治疗后第3、6、12个月进行随访,检测其TRAb及TGA、TMA浓度。结果治疗前TRAb及TGA、TMA水平高者,治疗后眼病获得改善的可能性较大;而治疗前TRAb及TGA、TMA水平低者,治疗后其活性变化不大,眼病的改善也不明显,差异有显著性。结论TRAb及TGA、TMA水平与突眼的发生和转归关系密切。更多还原

【Abstract】 Objective To discuss the prognosis of goggled-geye caused by Graves’ disease after treated with ¹³¹I and its association with the levels of TRAb,TGA and TMA in blood.Methods A total of 78 cases of Graves’ disease characterized by goggled-geye were treated with ¹³¹I,and visited at 3^rd,6^th and 12^th month after treatment.The blood levels of TRAb,TGA and TMA were tested before treatment and during follow-gup.Results The patients with high blood levels of TRAb,TGA and TMA before ¹³¹I treatment had a higher opportunity to get their eye symptoms improved,vice versa.There was a significant difference between the two kinds of patients.Conclusion The occurrence of goggled-geye and its turnover is closely related to the levels of TRAb,TGA and TMA.更多还原