【摘要】 目的:观察复方壬苯醇醚-9栓对家兔的抗生育作用和阴道刺激性。方法:采用改良Eckstein方法,对性成熟雌性家兔进行阴道刺激性研究。结果:家兔抗生育实验结果表明,高、中、低剂量实验药物组的避孕率分别为 100％、80％和60％;阴道刺激炎症总分值分别为4．3、3．5、3．0。结论:在实验应用剂量下壬苯醇醚-9抗生育作用及对阴道刺激性在可接受范围内。更多还原

【Abstract】 Objective: To observe effect of Nonoxynol - 9 compound suppository on antifertility and vaginal irritation in the rabbits. Methods: Female mature rabbits were taken an experimentation on vaginal irritation by the method of improved Eckstein. Results: Contraceptive rate in high, middle and low dose groups was 100% , 80% , 60% , respectively. Vaginal irritation score in three groups were4.3, 3.5, 3.0, respectively. Conclusion: Nonoxynol-9 compound suppository is antifertility and its irritation in the rabbit is acceptable.更多还原