【摘要】 目的采用随机分类方法,观察奥美拉唑和法莫替丁两种方法预防急性脑血管病并发应激性溃疡出血疗效。方法81例急性脑血管病患者随机分为奥美拉唑组43例,给予奥美拉唑40m g加入0.9%盐水或5%葡萄糖注射液100m l静脉点滴,维持30～60m in,1次d/,共10d;法莫替丁组38例,给予法莫替丁40m g加入0.9%盐水或5%葡萄糖注射液500m l维持静脉点滴24h,1次d/,共10d。结果两组并发应激性溃疡出血率:奥美拉唑组为16.2%,法莫替丁组为5.5%。两组差异无统计学意义(P>0.05)。结论两组方法预防急性脑血管病并发应激性溃疡出血疗效相似。更多还原

【Abstract】 Objective: To investigate and analyse the efficiency of omeprazole and famotide on the prevention of stress ulcer upper gastrointestinal bleeding followed apoplexy through a randomized clinical trial.Methods: Eighty one patients have been randomly divided into two groups,with forty three in the omeprazole group and thirty eight in the famotide group.In omeprazole group,they were given intravenous omeprazole 40mg added5% glucose of 0.9 sodium chloride 100ml daily,30～60 minutes for each injection,for ten days;in famotide group,the were given intravenous famotide 40mg added5%glucose or 0.9% sodium chloride 500ml daily,24 hours for each injection,for ten days.Results: In the two groups mentioned above,the rate of bleeding is 16.2%and 5.5% respectively,which shows no statistical significant differences in the two group(P>0.05).Conclusion The efficiency on the prevention of stress ulcer upper gastrointestinal bleeding followed apoplexy is similar in the two groups.更多还原