【摘要】 目的研制富马酸氯马斯汀凝胶剂,建立质量控制方法。方法用卡波姆-940为凝胶基质,用分光光度法测定含量,考察制剂的稳定性。结果该制剂均匀性、分散性好;含量测定平均回收率为99.78%,RSD为0.81%(n=3)。结论该制剂制备工艺简单,质量可控。更多还原

【Abstract】 Aim To study the prescription and preparation of Clemastine fumarate gel,and set up the method of control quality.Methods Carbopol-940 was used as base.The content was determined by spectrophotometry.The stability of Clemastine fumarate gel loas also investigated.Results The preparation was well-distributed.The average recovery of the Clemastine fumarate was 99.78%, RSD =0.81%( n =3).Conclusion The preparation process is simple and the quality can be controlled.更多还原