【摘要】 研究一种基于光固化快速成形技术的人工骨支架制备方法。设计空间结构的人工骨支架负型,利用立体光固化快速成形系统制造人工骨支架负型树脂原型,在人工骨支架负型树脂原型中填充β-磷酸三钙,通过热分解的方法去除SL原型,获得生物活性人工骨支架。研究了烧结与去除原型的方法,测得人工骨支架表面粗糙度分别是Ra=3.69,有利于细胞的黏附。进行体外细胞培养研究,发现成骨细胞能够在这人工骨支架上黏附生长,并向微管内生长,具有良好的生物学特性。更多还原

【Abstract】 The paper studies a method to fabricate the artificial bone scaffold based on the StereolithographySLtechnology. By designing the negative resin mold of the artificial bone scaffold for the spatial structure using SL system to make the negative resin mold for the artificial bone scaffold and fill the β-TCP into the negative resin mold of scaffold and removing the SL prototype through pyrolysis a bioactive artificial bone scaffold has been obtained. The approaches to sinter and remove the prototype have been studied. The surface roughness Ra of the artificial bone scaffold measured is 3.69μm which is favorable to cellular adhesion.更多还原