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Caspase与肝脏疾病
Caspase and liver diseases
【摘要】 近年来,细胞凋亡发生机制的研究日益受到人们的关注。研究表明,许多肝脏疾病与caspase家族有着密切联系,如肝缺血再灌注损伤、炎症、肿瘤等。现将细胞凋亡中caspase家族在肝脏疾病中的最新研究结果及其地位做了简单综述,希望由此了解肝细胞凋亡的内在机制并达到治疗目的。
【Abstract】 In recent years,the study about the mechanisms of cell apoptosis has been increasingly concerned.Many liver diseases are correlated with caspase family,such as hepatic ischemia/reperfusion injury、inflammation and cancer,etc.In the article,we reviewed the importance of caspase family and the new research on the mechanisms of hepatic cell apoptosis in liver diseases.Meanwhile,we summarized the evidence concerned with apoptosis,and discussed the knowledge of therapeutic strategies.
【关键词】 凋亡;
肝脏疾病;
caspase;
缺血再灌注损伤;
炎症;
【Key words】 apoptosis; liver diseases; ischemia/reperfusion injury; inflammation;
【Key words】 apoptosis; liver diseases; ischemia/reperfusion injury; inflammation;
- 【文献出处】 基础医学与临床 ,Basic & Clinical Medicine , 编辑部邮箱 ,2006年05期
- 【分类号】R575
- 【被引频次】8
- 【下载频次】200