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明胶软胶囊干燥特性的研究

Research on drying characteristics of soft gelatin-capsules

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【作者】 刘鸿雁王一平朱丽张及瑞

【Author】 LIU Hong-yan~(1,2),WANG Yi-ping~1,ZHU Li~1,ZHANG Ji-rui~2(1.School of Chemical Engineering and Technology,Tianjin University,Tianjin 300072,China;2.School of Chemical Engineering,Hebei University of Technology,Tianjin 300130,China)

【机构】 天津大学化工学院河北工业大学化工学院 天津300072河北工业大学化工学院天津300130天津300072

【摘要】 在对流干燥实验台上进行了明胶软胶囊干燥特性的实验,研究了加热空气温度、风速、湿度对干燥过程的影响规律。实验结果表明,提高加热空气的温度,虽然提高了传热速率,但在第2降速阶段干燥速率下降,导致最终含水质量分数反而偏高;随着加热空气风速的提高,传热速率增加,干燥速率在第1降速阶段呈现加快趋势,软胶囊的最终含水质量分数稍有降低;而加热空气湿度的变化,对传热过程影响很小,但随着加热空气湿度的降低,干燥速率提高,使得最终含水质量分数明显降低。通过研究软胶囊的干燥特性,为制药工业中软胶囊的生产提供合理指导,对优化干燥过程、降低能耗、提高产品质量和经济效益具有重要意义。

【Abstract】 In order to research the drying characteristics of soft gelatin-capsules,the experiment was engaged in convective drying apparatus.The surface temperature of soft gelatin-capsules was measured by an infrared thermal imager and the mass was tested by high accuracy electronic balance.The results show that with the increase of air temperature the rate of heat transfer increases,but the drying rate in the second falling period is decreased,which causes higher final water mass fraction in soft capsules;with the increase of the air velocity both the heat transfer rate and the drying rate in the first falling period increases,and the final water mass fraction of soft capsules is slightly dropped;the change of hot air humidity has very small influenced on heat transfer,but the drying rate(raises) as decreasing the air humidity,which leads to the obvious dropping of final water mass fraction in soft(capsules.) The experimental results can be used for guiding the manufacture of soft gelatin-capsules in the(pharmaceutical) industry.

  • 【文献出处】 化学工程 ,Chemical Engineering , 编辑部邮箱 ,2006年09期
  • 【分类号】TQ028.6
  • 【被引频次】8
  • 【下载频次】592
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