【摘要】 目的探讨联合应用小剂量阿司匹林、维生素E、乐力钙在预防子痫前期发病中的作用。方法选择子痫前期高危孕妇46例,将其随机分为治疗组及对照组各23例,治疗组每日给予阿司匹林75mg、维生素E100mg、乐力钙2.0g口服,至分娩。对照组按常规处理。结果无论是轻度或重度子痫前期,治疗组的发病率(13.0%)均显著低于对照组(39.1%)(P<0.05);治疗组早产率、死胎率及新生儿窒息发生率均显著低于对照组(P<0.05),而产后出血及胎盘早剥发生率在两组间无显著差异(P>0.05)。结论联合应用小剂量阿司匹林、维生素E、乐力钙对子痫前期的发生有着重要的预防价值。更多还原

【Abstract】 Objective To compare a combination treatment of low-dose aspirin,vitamin E and osteoform in women at high risk of preeclampsia.Methods 46 cases of preeclampsia high-risk women were classified into two groups randomly,treatment group 23 cases and control group 23 cases.Treatment group was treated with aspirin(75mg/d),vitamin E(100mg/d) and osteoform((2.0g/d)) throughout their pregnancies.Results The incidence(13.0%) of mild or severe preeclampsia in treatment group was markedly lower than that(39.1%) in control group(P<0.05);The incidence of premature delivery,fetal death and asphyxia of newborn in treatment group was markedly lower than that in control group(P<0.05);We found no differences between treatment group and control group in numbers of postpartum hemorrhage and placental abruption(P>0.05).Conclusion Our study gives supports to the notion that combination treatment of low-dose aspirin,vitamin E and osteoform is beneficial in women at high risk of preeclampsia.更多还原