【摘要】 目的探讨抗结核抗体检测在肺结核诊断中的临床意义,提高肺结核的诊断率。方法对162例活动性肺结核患者与166例非活动性结核患者进行抗结核抗体检测,活动性肺结核患者中涂阳与涂阴患者分组。分别用TB-Check-1一步免疫层析法进行抗结核抗体检测,分析比较组间的抗结核抗体阳性率和抗结核抗体联合痰涂片检查对活动性肺结核患者的诊断符合率的影响。结果活动性肺结核组的抗结核抗体阳性率显著高于非活动性肺结核组;活动性肺结核中涂阳与涂阴组间抗结核抗体阳性率无显著差异;抗结核抗体联合痰涂片检查特异性诊断符合率达56.8%,高于痰涂片诊断符合率30.9%。结论抗结核抗体检测可提高活动性肺结核的诊断率,抗结核抗体联合痰涂片检查提高特异性诊断符合率;抗结核抗体检测对痰涂阴性肺结核的诊断具有重要的临床意义。更多还原

【Abstract】 Objective To investigate the clinical significance of the TB anti-body in the clinical diagnosis of pulmonary tuberculosis,and to improve the diagnosis rate of the active pulmonary tuberculosis.Methods The examination of the TB anti-body with the patients including 162 cases of the active TB patients and 166 cases of the no-TB patients.To analyse and compare the positive rate of TB antibody between the two groups.To divide into two groups of positive sputum bacterium and negative sputum bacterium in 162 cases of the active TB patients.To investigate the diagnosis exact rate for the active TB by examination of TB anti-body and sputum bacterium.Results The positive rate of the TB anti-body in the active TB patients is higher significantly than that in no-TB patients.The positive rate is no significant difference between the positive sputum bacterium and negative sputum bacterium.The specific diagnosis exact rate(56.8%) of TB anti-body and sputum bacterium is higher than that(30.9%) of sputum bacterium.Conclusion The clinical diagnosis rate of the active pulmonary tuberculosis can be improved with examination of the TB anti-body.TB anti-body and sputum bacterium can be used to improve the specific diagnosis exact rate of the active pulmonary tuberculosis.This method has the important clinical significance in the TB diagnosis of the negative sputum bacterium.更多还原