【摘要】 目的:探讨非典型川崎病(KD)的发病情况及临床特点。方法:对2001年3月至2004年9月住院治疗的141例KD病例资料作回顾分析。结果:141例中113例(80·1%)为典型KD,28例(19·9%)为非典型KD。非典型KD组平均年龄1·33±1·65岁,较典型组小,差异有显著性(P<0·01);非典型KD只具备KD诊断标准中6项之4项或3项,非典型KD冠状动脉扩张(CAD)和冠状动脉瘤(CAA)的发生率为100%,与典型KD比较,差异有显著性(P<0·01);非典型KD组在病程8·9±6·8d接受丙种球蛋白治疗,住院天数为l5·3±6·6d,均较典型组的7·1±2·8d、11·5±5·7d明显延长,差异有显著性(P<0·05)。随访CAD大多数于3~6个月恢复正常。CAA于1年至2年恢复正常。结论:非典型KD更多见于小年龄的婴幼儿,非典型KD冠状动脉病变发生率高,冠状动脉病变是诊断非典型KD的重要依据,临床应重视早期诊断和早期治疗。更多还原

【Abstract】 Objective:To study the clinical characters of atypical Kawasaki disease (KD).Method:The data of 141 in-patients with Kawasaki disease from March 2001 to September 2004 were retrospectly analyzed.Results:There were 3 to 4 of 6 items of diagnosis standard in atypical KD.113 of 141 patients were typical KD and 28 cases of patients were atypical KD.The age in atypical KD was younger than that of typical KD and was significant deference compared to that of typical KD (P<0.01).The rate of incidences of coronary artery dilation (CAD) and coronary artery aneurism (CAA) in atypical KD was 100%,and were significantly deferent from that of typical KD (P<0.05).Time in hospital of atypical KD (l5.3±6.6d) was longer than that of typical KD (11.5±5.7d) and demonstrated significance compared to that of typical KD (P<0.01).The comeback of CAD will arises after 3 to 6 months,the same phenomena about CAA will happen after 1 to 2 years.Conclusion:The incidence of Atypical Kawasaki disease is higher in younger infant than that in older infant.The incidences of coronary artery dilation(CAD)is high in atypical KD,so it’s an important diagnose gist about this disease.更多还原