【摘要】 目的合成内酯型去甲二萜生物碱。方法塔拉萨敏经Jone’s氧化和Baeyer-V illiger氧化反应,合成了两种内酯型去甲二萜生物碱。单乙酰塔拉萨敏裂解C7-C17键后,经水解、Jone’s氧化、Baeyer-V illiger氧化及还原等共5步反应,合成了7,17-次裂的内酯型去甲二萜生物碱。结果和讨论所得产物的结构经MS1、HNMR和13CNMR确证。更多还原

【Abstract】 OBJECTIVE To synthesize lactone-type norditerpenoid alkaloids.METHODS Two kinds of lactone-type norditerpenoid alkaloids were synthesized from talatisamine as the starting material through Jone’s oxidation and Baeyer-Villiger oxidation.7,17-seco-lactone-type norditerpenoid alkaloids was prepared with the starting material 14-acetyltalatisamine through five steps.RESULTS and CONCLUSION The structures of the products were confirmed by MS,（）¹HNMR and（）¹³CNMR.更多还原