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天盾液对免疫低下小鼠免疫功能的影响
Effects of Tiandun solution on hypoimmunity mice immune system
【摘要】 目的研究天盾液对免疫低下模型小鼠免疫功能的调节作用。方法小鼠ip环磷酰胺,造成免疫功能低下的模型,观察天盾液对小鼠免疫器官重量、碳粒廓清能力、迟发型过敏反应、血清半数溶血素值(HC50)及脾细胞形成抗体功能的影响,盐酸左旋咪唑作为阳性对照。结果天盾液能显著增加免疫低下小鼠脾脏的重量,明显增强巨噬细胞的吞噬功能,提高绵羊红细胞所致的迟发型过敏反应和HC50水平;提升脾细胞分泌抗体的能力。结论天盾液能明显增强免疫功能低下小鼠的免疫功能。
【Abstract】 OBJECTIVE To study the immunomodulating effects of Tiandun solution on hypoimmunity mice.METHODS The experiment used hypoimmunity mice by Cyclohosphamide(ip).Weight of immune organs,ability of charcoal clearance,delayed allergic,serum 50% hemolytic value(HC50) and antibody forming of splenocyte were observed.Levamisole hydrochloride(LH) was selected as positive control.RESULTS The weight of thymus and HC50 value increased significantly,the phagocytic function of macrophage,delayed allergic response and antibody forming of splenocyte were also strengthened.CONCLUSION The immune suppression of hypoimmunity mice were improved by Tiandun solution obviously.
【Key words】 Immunity regulation; Tiandun solution; Charcoal clearance; Hemolysin; Delayed allergic response;
- 【文献出处】 华西药学杂志 ,West China Journal of Pharmaceutical Sciences , 编辑部邮箱 ,2006年03期
- 【分类号】R285
- 【被引频次】1
- 【下载频次】116