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5-(3-吡啶基)-2-芳氧乙酰胺基-1,3,4-噻二唑的合成、晶体结构及生物活性
Synthesis,crystal structure and biolgical activity of 2-aryeoxyacetylamido-5-(3-pyridyl)-1,3,4 -thiadiazoles
【Abstract】 Six derivatives of 2-aryloxyacetylamido-5-(3-pyridyl)-1,3,4-thiadiazoles 3a ~3f have been synthesized by thereactions of 2-amino-5-(3-pyridyl)-1,3,4-thiadiazoles and aryloxyacetyl chloride.Their structures were characterizedby1HNMR,IR and elemental analysis.The crystal st ucture of 3d was determined by X-ray single crystal diffraction.The crystal ofthis compound belongs to moncolinic system with space group P21/c,a =0.76550(7)nm,b =0.90221(8)nm,c =2.2927(2)nm,β=92.811(2)°,V=1.5816(2)nm3,Z =4,Dc=1.601g/cm3,μ=0.559mm-1,F(000) =776,R1=0.0419,wR2=0.1216.Thepreliminary biological activity tests showed that some title compounds have relatively good activity as plant growth regulator.
【关键词】 噻二唑;
合成;
晶体结构;
生物活性;
【Key words】 thiadiazole; synthesis; crystal structure; biological activity;
【Key words】 thiadiazole; synthesis; crystal structure; biological activity;
【基金】 国家自然科学基金项目(20072009)资助;湖北省教育厅青年项目(Q200529003)资助
- 【文献出处】 化学研究与应用 ,Chemical Research and Application , 编辑部邮箱 ,2006年04期
- 【分类号】O626.2
- 【被引频次】3
- 【下载频次】200