【摘要】 利用简便易得的N-取代苄基芳胺的汞化产物,经亚硝化反应得到8种N-取代苄基-N-亚硝基-2-乙酸汞基芳胺,并通过分子内缩合合成了一种苯并咪唑衍生物,其结构经元素分析、1HNMR、IR及X射线单晶衍射确证。此方法为合成咪唑类化合物提供了一条新途径。更多还原

【Abstract】 Eight kinds of 2-acetomercuri-N,N-（nitroso-4′-substituted benzyl） arylamines were synthesized in high yield by nitrosation of corresponding 2-acetomercuir-N-（4′-substituted benzyl） arylamines and characterized by IR, ¹H NMR, elemental analysis, and the compound 2f was further confirmed by X-ray crystal structure determination. The intramolecular rearrangement-condensation reaction of compounds 2e was carried out in HCl/H₂O/EtOH to yield 2-（4′-chlorophenyl）-5-methoxybenzimidazole （3）, and the possible reaction mechanism was proposed.更多还原