【摘要】 以对苯二甲酸和碘为原料,50%发烟硫酸为溶剂,制得2,3,5,6-四碘对苯二甲酸,再通过氯化亚砜进行酰氯化,最后与葡甲胺反应合成了标题化合物。其结构通过元素分析、红外光谱、核磁共振氢谱,质谱得到确证。运用正交实验优化了酰胺化反应条件:三乙胺为缚酸剂,四碘对苯二甲酰氯和葡甲胺为反应物,它们的物质的量比为2.1∶1∶2.4,反应温度为40℃时,产率高达71.5%。更多还原

【Abstract】 N,N′-Bismethyl-N,N′-bis-(2,3,4,5,6-pentahydroxyhexyl)-2,3,5,6-tetraiodoterephthal-amide is synthesized by iodination of terephthalic acid,acyl chloride and amdiation.Their structures were identified by elemental analysis,IR,MS and 1HNMR.Under the optimal reaction conditions triethylamine∶tetraiodoisophthalic acid dichloride∶N-methylglucamine=2.1∶1∶2.4,reaction temperature is 40℃,the yield is 71.5%.更多还原