【摘要】 自2000年以来,具有可消除性的LbL膜因其在药物缓释领域的重要应用前景而逐渐受到广泛关注。本文总结归纳了这一新颖领域中的一些重要的前驱性工作,发现目前的可消除膜还存在两个尚待解决的问题:消除速度无法精确控制;消除条件较为苛刻。针对这些现象,文中例举了作者自己的一个相关工作,经过分析探讨,发现在非常温和的条件下,PTAA/PVP膜能够缓慢且持久地消除。更多还原

【Abstract】 Since 2000,erasable layer-by-layer(LbL) films have received much attention for their potential application in the functional delivery system.Several premonitory but significant works in this novel research field are briefly reviewed in this contribution.Two kinds of drawbacks in the above-mentioned systems,namely,"uncontrollable release rate" and "relatively strict condition to release" are summarized.Part of the new work of the authors in this field is also discussed,and the results show that PTAA/PVP films can release mildly and continuously in the neutral aqueous solution.更多还原