【摘要】 以二氯亚砜(SOCl2)为催化剂,通过罗丹明B和异丙醇反应合成了异丙罗丹明B酯。在实验过程中,采用簿层色谱对反应进行跟踪,研究了反应温度和反应时间等因素对罗丹明B酯化速度和转化率的影响,确定了较佳的反应条件:催化剂为SOCl2,反应温度为70℃、反应时间为7 h。采用柱层析分离,展开剂为C2H5OH/CH2Cl2=2∶1(体积比)。经过此法合成、提纯的异丙罗丹明B酯的纯度达到98.2%,总收率达到83%。更多还原

【Abstract】 Isopropylrhodamine B was obtained from esterification of Rhodamine B and isopropyl alcohol,in the presence of sulfinyl chloride（SOCl₂）.The reaction is monitored by thin layer chromatography（TLC）.The effect of reaction temperature and time on the esterification rate and conversion rate of Rhodamine B were examined.The suitable reaction condition was SOCl₂ as catalyst,reaction temperature of 70 ℃ for 7 h.The isopropylrhodamine B was dissolved in dichloromethane and purified by column chromatography（ethanol/dichloromethane=2∶1（volume））.In this method,the result showed that the purity of isopropylrhodamine B was 98.2% and the overall conversion rate was 83%.更多还原