【摘要】 目的观察非体外循环(OPCAB)与常规体外循环冠状动脉旁路移植术(cCABG)围手术期心肌肌钙蛋白I(cTnI)及肌酸磷酸激酶同功酶(CK-MB)的变化规律,探讨其在心肌损伤诊断方面的价值。方法OPCAB组与cCABG组患者各40例,术前、术后即刻、术后第1d、2d、3d、4d、5d、6d、7d、10d晨采静脉血标本检测血清cTnI、CK-MB。结果OPCAB组与cCABG组术后cTnI、CK-MB均有不同程度升高,然后逐渐下降至正常;cTnI高于正常的持续时间长于CK-MB;OPCAB组较cCABG组cTnI、CK-MB浓度峰值低,恢复正常所需时间短(P<0.05或0.01)。结论OPCAB与cCABG术后cTnI与CK-MB变化规律相似,且cTnI的诊断时间窗宽于CK-MB。更多还原

【Abstract】 Aim: To investigate perioperative changes of cardiac troponin I(cTnI),CK-MB and their efficacy in diagnosing myocardial injury in off-pump cornary artery bypass(OPCAB)and conventional cornary artery bypass grafting(cCABG). Methods: A total of 40 cases of OPCABs and 40 cases of cCABGs were collected. Venous blood samples were taken at just before and after operation, the 1st,2nd,3rd,4th,5th,6th,7th,10th d for assessing cTnI and CK-MB.Results: In both groups, cTnI and CK-MB increased at different levels after operation and decreased to normal level, however, the levels of cTnI and CK-MB in OPCAB were lower than those of cCABG. Conclusion: Changes of cTnI and CK-MB are similar after OPCAB and cCABG, and cTnI is of larger diagnostic time window.更多还原