【摘要】 目的:探讨子宫内膜癌发病的可疑危险因素。方法:采用1∶1配比病例对照研究方法,对120例病例和120例对照进行有关体重、月经史、婚育史、既往史、家族史等因素的调查分析。结果:单因素分析表明,体重、身体健康状况、高血压史、冠心病史、其他妇科病史、其他肿瘤病史、初潮年龄、月经周期紊乱、月经量、是否绝经、不孕不育史、流产与子宫内膜癌的发病有关。通过多因素Logistic逐步回归分析,最终引入回归方程的变量为不孕不育史、月经周期紊乱、身体健康状况、冠心病史、初潮年龄、是否绝经。结论:不孕不育史、月经周期紊乱、身体健康状况差、冠心病史为子宫内膜癌的危险因素,而初潮年龄晚、已绝经为子宫内膜癌的保护因素。更多还原

【Abstract】 Objective To investigate the questionable risk factors of endometrial cancer.Methods A 1∶1 matched case-control study was conducted.120 cases with endometrial cancer and 120 controls were interviewed using a questionnaire,including body mass,menstrual history,marital and pregnancy histories,past history,family history,etc.Results The monovariate analysis results showed that body mass,physical condition,hypertension history,coronary heart disease,gynecological history,phymatosis history,menarche age,menstrual disorder,menstrual blood volume,menopause status,infertility history and miscarriage were associated with endometrial cancer.While multivariate conditional logistic regression analysis discovered that the risk factors of endometrial cancer would include infertility history,physical condition,coronary heart disease,menarche age,menopause status and menstrual disorder.Conclusion Infertility history,menstrual disorder,physical condition and coronary heart disease increased the risk of endometrial cancer,but later menarche age and menopause were associated with reduced risks of endometrial cancer.更多还原