【摘要】 乙二醛和苄胺在酸的催化作用下发生醛胺缩合反应,可以合成高张力笼形氮杂环化合物六苄基六氮杂异伍兹烷(HB IW),但产物中含有少量副产物。采用柱色谱将其分离,通过FT-IR、1HNMR、ESI-MS、元素分析测定一种杂质为N,N′-二苄基乙二酰胺。用苄胺和草酰氯在甲苯和吡啶的混合溶剂中合成出N,N′-二苄基乙二酰胺,并利用光谱分析对合成的目标化合物的结构进行了表征,与柱色谱分离得到物质的谱图相一致,进一步说明HB IW合成反应的副产物就是N,N′-二苄基乙二酰胺。更多还原

【Abstract】 The impurity N,N′-dibenzyl-oxalmide in 2,4,6,8,10,12-hexabenzyl-2,4,6,8,10,12-hexaazateracycle[5.5.0.0^5,9.0^3,11]dodecanes（HBIW） prepared by glyoxal and benzylamines was separated by column chromatography and identified by FTIR,（（）¹HNMR）,MS and elemental analysis.Futhermore,N,N′-dibenzyl-oxalamide was synthesized with benzylamines and oxalyl chloride,and identified by spectrometric analysis which verified that the impurity was the N,N′-dibenzyloxalamide.更多还原