节点文献
1-O-烯丙基-4-羟基蒽醌与牛血清白蛋白相互作用的电化学研究(英文)
Electrochemical Study of the Interaction of 1-O-allyl-4-hydroxyanthraquinone with Albumin
【摘要】 采用循环伏安法研究了1-O-烯丙基-4-羟基蒽醌(OAHAQ)的电化学行为.研究表明,OAHAQ与BSA能形成了1:1的配合物,同时研究了OAHAQ及其与BSA配合物的表观扩散系数,在BSA存在下,OAHAQ的标准速率常数Ks没有显著的变化,其还原峰电流随着BSA的加入而减小,据此可用来测定BSA的浓度.
【Abstract】 The electrochemical behavior of 1-O-allyl-4-hydroxyanthraquinone(OAHAQ) in an aqueous medium was investigated.OAHAQ can form adducts with albumin(BSA).The apparent diffusion coefficients of OAHAQ and OAHAQ-BSA adduct and the stoichiometry of OAHAQ and BSA in OAHAQ-BSA adduct were measured.In the presence of BSA,the standard rate constant Ks of OAHAQ was not significantly changed.The reduction peak current of OAHAQ decreased with the addition of BSA in the solution.The proposed method can be operated to probe the interaction between these species and to determine BSA.
【Key words】 Adduct of OAHAQ and BSA; Cyclic voltammetry; Determination of BSA;
- 【文献出处】 湖南城市学院学报(自然科学版) ,Journal of Hunan City University(Natural Science) , 编辑部邮箱 ,2006年03期
- 【分类号】Q51
- 【下载频次】50