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新型抗哮喘药物环索奈德的合成
Synthesis of New Antiasthma Drug of Ciclesonide
【摘要】 使用新的方法合成了环索奈德。以泼尼松龙为原料,用新的催化剂改进了17α羟基的酯化方法,优化了产品的重结晶方法。降低了成本易于工业化生产。
【Abstract】 Ciclesonide was synthesized using a new method.Prednisolone was used as basic material,and new catalyst was used to improve esterification of 17α—OH.The method of recr ystalization has been improved.The process is easy,reducing the cost and suitable for industrial manufacture.
- 【文献出处】 化工时刊 ,Chemical Industry Times , 编辑部邮箱 ,2006年05期
- 【分类号】TQ467
- 【被引频次】3
- 【下载频次】381