【摘要】 目的:观察曲美布汀加喜普妙治疗功能性消化不良的疗效。方法:154例FD患者随机分为两组,观察组81例,给予曲美布汀胶囊及喜普妙联合用药治疗;对照组73例,单用曲美布汀治疗。比较观察两组的上腹胀满、餐后饱胀、早饱等症状的变化。结果:观察组对照组用药4周后临床主要症状均明显缓解(P<0.01或0.05);除呕吐及上腹部疼痛外,其他症状消失率观察组均优于对照组。观察组治疗总有效率为91.3%,对照组为75.3%,两组相比,差异有显著性意义(P<0.05)。两组患者均无严重的不良反应。结论:曲美布汀联合喜普妙治疗FD疗效好,耐受性好,是一种可靠可行的治疗FD的方案。更多还原

【Abstract】 Objective: To study the effect of Trimebutine and Citalopram in the treatment of functional dyspepsia(FD).Methods: 154 FD paitients were randomly divided into two groups.The observation group(n=81) were given 100mg Trimebutine(3 time a day) and 20mg Citalopram(once a day) while the control group(n=73) were given 100mg Trimebutine(3 time a day),for 4 weeks.Clinical symptoms were compared.Results:The main clinical symptoms in both groups were significantly relieved after 4-week treatment(P<0.011 or 0.05).The other symptoms except vomiting and upper abdominal pain disappeared more completely in observation group than in control group.The total effective rates were 91.3% and 75.3% in observation group and contrl group,respectively.The difference between groups was significant(P<0.05).There was no severe side effect in both groups.Conclusion: The therapeutic effect of Trimebutine combined with Citalopram in treating FD is satisfactory and safe.更多还原