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平阳霉素瘤体内注射治疗小儿体表血管瘤的临床研究

Clinical Study of Intratumoral Pingyangmycin Injection for Hemangiomas in Children

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【作者】 郑俊鸿李林芬林静霞李建宏肖诺茵

【Author】 ZHENG Jun-hong, LI Lin-fen, LIN Jing-xia,et al(The 2nd Affiliated Hospital to Shantou Univ.Medical College,Guangdong Shantou 515041,China)

【机构】 汕头大学医学院第二附属医院外科汕头大学医学院第二附属医院外科 广东汕头515041广东汕头515041

【摘要】 目的:探讨采用平阳霉素行小儿体表血管瘤注射的临床疗效及安全性。方法:将平阳霉素配为1%浓度,用带第4号针头注射器吸取适量药液,根据血管瘤大小直接注射至瘤体内,直至瘤体表面发白肿胀为止。每1~2周注射一次,每次量不超过6mg。结果:182例患者经平阳霉素注射治疗后,随访3个月到1年。治愈率49.5%、显效率38.5%、总有效率88%。除部分患儿注射局部肿痛外,全身不良反应轻微。结论:平阳霉素瘤体内注射治疗小儿体表血管瘤疗效确切,副作用小、安全可靠。

【Abstract】 Objectives: To observe the efficacy of pinyanmycin injection for superficial hemangiomas in children.Methods: Pingyangmycin was intratumorally injected to the hemangioma mass at the concentration of 1% until the mass had become pale and swollen once two weeks for 3~5 times.Results: 182 children received pingyangmycin injection and were followed for 3 months to 1 year.The cure rate was was 49.5%,and the effectiveness rate was 38.5%.Therefore,the total effectiveness rate was 88%.The complication was minimal.Conclusions: Intratumoral injection of pingyangmycin was a safe,convenient and effective therapeutic modality for superficial hemangioma in children.

【关键词】 平阳霉素血管瘤注射治疗
【Key words】 PingyangmycinHemangiomaInjection
  • 【分类号】R732.2
  • 【被引频次】3
  • 【下载频次】76
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