【摘要】 目的比较P63及k19在标记人角膜缘干细胞相对特异性的高低。方法使用免疫组织化学法检测P63及k19在人角膜中央上皮细胞及角膜缘干细胞的分布情况。结果在人角膜缘干细胞P63少量表达、k19大量表达;角膜中央上皮细胞P63基本没有表达、k19仍有少量表达。结论P63作为人角膜缘干细胞标记物的特异性高于k19。更多还原

【Abstract】 Objective To compare the specificity of P63 and k19 as a marker of human cornea limbic stem cells.Methods The expression of P63 and k19 was observed with the technique of immunohistochemistry.Results Few cornea limbic stem cells expressed P63 and a lot of them expressed k19;central corneal epithelium cells didn’t express P63,however,some of them expressed k19.Conclusion As a marker of human cornea limbic stem cell,P63’s specificity is higher than that of k19.更多还原