【摘要】 目的探讨超声造影二次谐波成像技术在肝肿瘤诊断中的价值。方法31例肝肿瘤患者经肘静脉团注SonoVue,采用超声造影二次谐波成像技术,实时观察注射造影剂后病灶增强特征。结果经超声造影后,23个肝血管瘤动脉相均呈高回声增强,20个表现为周边向心型,2个为中央扩散型,1个为整体型增强特征;20个病灶在门脉相和延迟相仍为高回声增强,2个病灶渐变为等回声增强,1个病灶渐变为低回声增强。4个肝细胞癌动脉相呈高回声整体增强,门脉相1个呈等回声增强,3个呈低回声增强,延迟相均呈低回声增强。4个肝转移癌动脉相呈高回声增强,1个呈不均匀增强,3个呈环状增强,门脉相和延迟相均呈低回声增强。结论SonoVue超声造影二次谐波成像技术能动态显示病灶增强特征,有助于肝肿瘤的诊断及鉴别诊断。更多还原

【Abstract】 Objective To investigate the value of SonoVue contrast-enhanced ultrasound and second harmonic imaging in diagnosing liver neoplasms.Methods SonoVue was bolus injected via peripheral vein of thity-one patients with liver neoplasms.The technique of contrast-enhanced ultrasound and second harmonic imaging were used to observe the enhancement features of lesions after injection of SonoVue.Results All hemangiomas revealed hyper-enhancement during arterial phase and 20 cases of them showed periphery to center enhancement pattern,2 cases showed center to periphery enhancement pattern,1 cases revealed homogeneous enhancement pattern.20 cases showed hyper-enhancement,2 cases lesions showed iso-enhancement and 1 rervealed hypo-enhancement in portal phase and late phase;4 cases hepatocellular carcinoma showed hyper-enhancement and homogeneous enhancement pattern during arterial phase.1 revealed isoenhancement and 3 cases showed hypo-enhancement in the portal phase.4 cases revealed hypo-enhancement in late phase;4 cases liver metastasis revealed hyper-enhancement and 1 cases showed inhomogeneous enhancement,3 cases showed ring enhancent in arterial phase.4 cases revealed hypo-enhancement in the portal phase and late phase.Conclusion The SonoVue contrast-enhanced ultrasound and second harmonic imaging reveals dynamic enhancement features of liver neoplasms,which is helpful to the diagnosis and differential diagnosis.更多还原