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武汉地区脂肪肝的流行现状及危险因素分析

Study of the Prevalence Rate and Risk Factors of Fatty Liver in Wuhan City

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【作者】 王中丽夏冰陈向群刘源朱艳萍余兰

【Author】 WANG Zhongli~1,XIA Bing~1,CHEN Xiangqun~2,LIU Yuan~1,ZHU Yanping~1,YU Lan~1~1Dept.of Internal Medicine and Geriatrics & Research Center of Digestive Diseases,Zhongnan Hospital of Wuhan University,Wuhan 430071,China~2Key Laboratory of Allergy and Immune-related Diseases,School of Medicine,Wuhan University,Wuhan 430071,China

【机构】 武汉大学中南医院综合医疗科/消化系病研究中心武汉大学医学院过敏与免疫相关疾病重点实验室武汉大学中南医院综合医疗科/消化系病研究中心 武汉430071武汉430071

【摘要】 目的:研究脂肪肝及脂肪性肝炎的流行现状与危险因素。方法:随机抽取湖北省武汉市水果湖地区体检人员3 649人,测定体重指数(BMI),检测空腹血糖(FBS)、谷丙转氨酶(ALT)、胆固醇(TC)、甘油三脂(TG)等生化指标及肝脏B超。结果:共检出脂肪肝913人,患病率为25.01%,其中男722例(79.1%),女191例(20.9%)。脂肪肝发生随年龄上升而上升,男性50-60岁患病率最高,女性60-70岁最高。脂肪肝随BMI上升而上升,体重、身高资料齐全者880人,超重者及肥胖者808例(91.8%),其中肥胖者占68.1%。脂肪肝伴发高血压病者214例(23.4%),空腹血糖大于6.1 mmd/L者258例(28.3%),高血脂症者604例(66.2%)。脂肪性肝炎发病率6.4%。结论:随着生活水平的提高,城市脂肪肝发病率直追发达国家,男性明显大于女性,60岁以后女性发病率大于男性。男性、高脂血症、肥胖、高血压、糖代谢紊乱为脂肪肝危险因素。

【Abstract】 Objective: To investigate the prevalence rate and risk factors of fatty liver in Wuhan city,China.Methods: The study involves 3 649 persons in Wuhan Shuiguohu area of Hubei province and their height,weight,limosis blood suger,alanine aminotrans ferase(ALT),total cholesterin(TC),total glycerin(TG)and ultrasonographic results were recorded and analyzed.Results: There have 913 cases of fatty liver in our study,with 722(79.1%) males and 191(20.9%) females.The total incidence of fatty liver was 25.0%.The fatty liver incidence increased with age.The highest incidence of male fatty liver was in 50-60 years group,and that of the female was in 60-70 years group.The fatty liver increased with BMI.In our study,808 cases(91.8%) had overweight and adiposity,and 599 cases(68.1%) had adiposity.The incidence of steatohepatitis was 6.4%.Conclusion: With the improving of living condition,city incidence of fatty liver is increasing to the level of developed countries.The male incidence is higher than female except for the population of 60 years old or older.Male,dyslipid,obesity,hypertension and fasting hyperglycemia are risk factors of fatty liver.

【关键词】 脂肪肝流行病学患病率危险因素
【Key words】 Fatty LiverEpidemiologyPrevalenceRisk Factor
  • 【文献出处】 武汉大学学报(医学版) ,Medical Journal of Wuhan University , 编辑部邮箱 ,2006年03期
  • 【分类号】R575.5
  • 【被引频次】30
  • 【下载频次】212
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