【摘要】 提出了在酸性条件下左氧氟沙星-Ce(Ⅳ)-Na2S2O4化学发光新体系,探讨了该化学发光体系的发光机理.建立了测定左氧氟沙星的流动注射化学发光分析新方法.方法的检出限为7×10-9g/mL,线性范围为2×10-8~6×10-6g/mL,11次平行测定质量浓度为6×10-7g/mL的左氧氟沙星,其相对标准偏差为2.0%.测定了左氧氟沙星注射液和片剂及血清和尿液中左氧氟沙星的含量,回收率为98.4%~103.7%,结果令人满意.更多还原

【Abstract】 A new chemiluminescence system,levofloxacin-Ce（Ⅳ）-Na-2S-2O-4-H-2SO-4,was developed for the determination of levofloxacin.The chemiluminescence mechanism of the system was discussed.A new chemiluminescence detection method combined with flow injection was described for the determination of levifloxacin in body fluid and pharmaceutical preparations.The detection limit for levofloxacin is 7×10^-9 g/mL,and the relative standard deviation（n=11） is 2.0% at 6×10^-7 g/mL.The linear range is 2×10^-8～6×10^-6 g/mL.The method has been applied to the determination of levofloxacin in body fluid and pharmaceutical preparations with satisfactory results.更多还原