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牛蒡子口腔崩解片的处方研究

Design of Rapidly Disintegrating Oral Tablet with Arctium lappa L.

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【作者】 龚又明刘利根赵浩如高妮

【Author】 GONG You-ming~1,LIU li-gen~1,ZHAO Hao-ru~1,GAO Ni~2(1.Department of Traditional Chinese Medical in China Pharmaceutical University,Nanjing,210038,China;2.Guangzhou School of Pharmacy,Guangzhou,510430,China)

【机构】 中国药科大学中药学院广州市医药中等专业学校 南京210038南京210038广州510430

【摘要】 目的确定牛蒡子口腔崩解片的处方。方法采用正交设计法选择牛蒡子口腔崩解片的处方。结果确定牛蒡子口腔崩解片处方中主要的成分配比为:交联聚乙烯吡咯烷酮8%,微晶纤维素25%,α-乳糖25%。结论确定了牛蒡子口腔崩解片的处方,但是此片剂口感一般,须进一步研究。

【Abstract】 OBJECTIVE To determine the formulation of the rapidly disintegrating oral tablet of Arctium lappa L.METHODS Formulae of the rapidly disintegrating oral tablet were selected with a method of orthogonal design.RESULTS The percentage of the major ingredients in the formulation of the tablets was determined;PVPP8%,MCC 25%,and α-lactose 25%.CONCLUSION The formulation of the oral tablets was optimized.Since the taste of the medication was not good enough,Studies on palatability should be carried out in the nest step.

  • 【文献出处】 海峡药学 ,Strait Pharmaceutical Journal , 编辑部邮箱 ,2006年01期
  • 【分类号】TQ461
  • 【被引频次】4
  • 【下载频次】175
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