【摘要】 目的观察腰椎穿刺(腰穿)脑脊液置换加鞘内注射地塞米松治疗高血压性脑出血破入脑室的临床价值。方法设治疗组30例和对照组28例。两组入院后均给予常规药物治疗;治疗组在24h内施行第一次腰穿脑脊液置换术,并予鞘内注射地塞米松,每天1次,共3～5次。结果治疗组总有效率93.3%,对照组总有效率78.6%,经统计学处理差异有极度显著性(P<0.01)。结论采用脑脊液置换加鞘内注射地塞米松治疗高血压性脑出血破入脑室疗效好,且简便安全易操作。更多还原

【Abstract】 Objective To survey the clinical therapeutic effect of cerebrospinal fluid(CSF) displacement by lumbar puncture and intrathecal injection of dexamethasone in the treatment of hypertensive intracerebral hemorrhage(HICH) into partial ventricles of the brain. Methods Patients in both treatment group and control group were given routine remedies after admission to our hospital. Within 24h after admission,patients of the treatment group were subjected to the first displacement of CSF by lumbar puncture. Briefly the procedure was as follows. Approximately 6ml of CSF were let to drop out from the puncture needle and an equal amount of 0.9% sodium chloride solution was injected into the subarachnoid space. The procedure was repeated for several times until 20-30ml of bloody CSF were displaced. Last,intrathecal injection of dexamethasone,CSF displacement and intrathecal injection of dexamethasone were carried out daily for 3-5 consecutive days. Results The total effective rate was 93.3% in patients of the treatment group and 78.6% in those of the control group. The difference was statistically highly significant(P<0.01). Conclusions CSF displacement by lumbar puncture and intrathecal injection of dexamethasone were found to have a good effect in the treatment of HICH into partial ventricles of the brain. The procedure is safe and easy to operate.更多还原