【摘要】 由柠檬酸和正丁醇在复合催化剂存在下合成柠檬酸三丁酯。它再与醋酐于复合催化剂下合成乙酰柠檬酸三丁酯。酯化反应的最佳条件为:柠檬酸与正丁醇的物质量之比为1:3．5,于100℃～130℃反应,催化剂质量为柠檬酸的0．8％,反应时间2．8 h,酯化率>99．4％,纯度>99．5％;乙酰化最佳反应条件为:柠檬酸三丁酯与醋酐物质的量之比为1:1．4,于60℃～85℃反应时间为1．4 h,催化剂用量为柠檬酸三丁酯的0．01％(质量),乙酰化转化率>99．5％,纯度为99.5％。更多还原

【Abstract】 Non - toxic tributyl citrate was synthesized by citric acid and n - butanol. The non - toxic acetyl tributyy citrate was synthsized by tributyl citrate and acetyloxide in the presence of compounded catalyst. The optinum esterification conditions were determined as follows: molar ratio of citric acid to n - butanol was 1:3. 5, reaction temperature 100℃~ 130℃, quantity of catalyst accounted for 0.8 % of citric acid and reaction time was 2. 8 hs.The final conversion of more than 99.4 % with a purity of more than 99.5 % . The optinun acetyla-tion conditions were determined as follows: molor ratio of tributyl citrate to acetyloxide was 1:1.4, reaction temperature 80℃~ 85℃, reaction time 1.4 hs, quanitiy of catalyst accounted for 1 % of tributyl citrate. Resulted in final conversion of more than 99. 5 % . The optinun acetylation conditions were determined as follows:molor ratio of tributyl citrate to acetyloxide was 1:1. 4, reaction temperature 80℃-85℃, reaction time 1.4 hs, quantity of catalyst accounted for 1 % of tributyl citrate. Resulted in final conversion of more than 99. 5 % with a purity of more than 99.5 % .更多还原