【摘要】 目的分析大段同种异体骨移植在四肢骨肿瘤瘤段切除后大段骨缺损中的疗效。方法对35例四肢骨肿瘤,按Enneking分期原则确定切除范围,进行瘤段广泛切除,大段异体骨移植修复骨缺损,并辅以坚强内固定,高恶性骨肿瘤则进行术前、后化疗。结果随访7～65个月,治疗满意率为75%,主要并发症是感染、不愈合、骨折、局部复发、肺转移死亡,其发生率为30%,保肢率为77%。结论大段同种异体骨移植是治疗四肢骨肿瘤瘤段切除后骨缺损的一种有效可行的方法。更多还原

【Abstract】 Objective To study the effect of massive frozen allograft in reconstruction of bone defects in extremities. Methods 35 patients with tumor underwent massive resections and massive allograft reconstruction of bone defects of extremities Internal fixation were used in all patients. Some high malignant tumor underwent adjunctive and neoadjuvant chemotherapy. Results All patients were fellow-up for 7-65 months and satisfactory rate was 75%. The main complications were infection, no-union, re-fracture, local tumor recurrence and lung metastasis The complication rate was 30% and salvage extremities rate was 77%. Conclusions The massive allograft is good for reconstruction of defects after bone tumor resections in limb.更多还原