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不同海拔高度人群牙龈及龈沟液中IL-8含量的检测

Level of IL-8 in Gum and Gingival Crevicular Fluid in Altitude Population

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【作者】 李子坤; 田广庆; 张志清; 周泉;

【Author】 Li Zikun,Tian Guangqing,Zhang Zhiqing,Zhou QuanQinghai Provincial People’s Hospital

【机构】 青海省人民医院口腔科; 青海省人民医院口腔科 810007; 810007;

【摘要】 目的:探讨不同海拔高度人群牙龈及龈沟液中IL-8含量。方法:应用免疫荧光检测法测得检测值并用Studentt检验进行统计学处理。结果:广州、西宁两地牙龈及龈沟液IL-8的检出率均明显高于青海玉树结古。结论:高原缺氧、营养物质缺乏、饮食单调、末梢循环差等因素均可导致宿主免疫力低下而导致牙龈及龈沟液IL-8含量低于广州、西宁。海拔高度有影响。

【Abstract】 Objective: To examine the content of IL-8 in gum and gingival crevicular fluid in Tibetan and Hah nationality at different altitude. Methods: The level of IL—8 in population,who have been living in Guangzhou city(2m altitudes),Xining city(2 260m altitudes) and Yushu nation(3 800m altitudes) respectively,was measured by immunofluorescence detection;the results were analyzed by statistical treatment of Student and t test.Results: The positive rate of IL-8 in gum and gingival crevicular fluid in Guangzhou and/or Xining was significantly higher than that in Yushu,there was a difference(P<0.05).Conclusions: There is a lower level of IL-8 in human with higher altitude due to hypoxia and other reasons.

【关键词】 海拔高度; 牙龈; 龈沟液; 白介素-8;
【Key words】 High altitude; Gum; Gingival crevicular fluid; IL-8;
  • 【文献出处】 高原医学杂志 ,Journal of High Altitude Medicine , 编辑部邮箱 ,2006年04期
  • 【分类号】R78
  • 【被引频次】12
  • 【下载频次】51
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