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Epstein-Barr病毒相关疾病的研究现状

Current Advance of Study on Epstein-Barr Virus-associated Diseases

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【作者】 戚东桂刘荣

【Author】 QI Dong-gui LIU Rong(The Second Clinical Department,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China)

【机构】 华中科技大学同济医学院2000级七年制科研小组华中科技大学同济医学院2000级七年制科研小组 430030武汉(硕士研究生)430030武汉(硕士研究生)

【摘要】 自1964年Epstein和Barr在研究非洲儿童恶性淋巴瘤时发现EB病毒以来,人类对EB病毒的研究不断深入,对其特性有了一定的认识,发现其与多种疾病有关,如鼻咽癌、淋巴瘤、传染性单核细胞增多症等,特别是EB病毒的分子生物学特性、EB病毒抗原所引起的免疫应答与免疫逃避在疾病中的发生发展中发挥着重要的作用,而且EB病毒在不同疾病中的感染类型及发病机理也不完全相同,因而对其致病机制进行深入地探讨很有意义。

【Abstract】 Since the discovery of EB virus, we have accumulated more and more information about it .So for, it has been found that many diseases are related to it such as nasopharyngeal carcinoma,lymphoma,infectious monorucleosis and so on and the pathogentic roles of EB virus have been researched intensively, especially,the molecular biology specificity of EB virus, immune response and the immune evasion induced by EB viruss antigen all paly importemt roles in disease development and progression. Pathogenesis and the type of infection differ in diseases that were caused by EB virus.

【关键词】 EB病毒淋巴瘤鼻咽癌
【Key words】 EB virusLymphomaNasopharyngeal carcinoma
  • 【文献出处】 国际免疫学杂志 ,International Journal of Immunology , 编辑部邮箱 ,2006年04期
  • 【分类号】R363
  • 【被引频次】44
  • 【下载频次】563
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