【摘要】 选择6种大孔吸附树脂(AB-8,NKA-9,NKA-Ⅱ,DA-201,D-101,D 001)分离提取大叶钩藤(Uncar iam acrophy llaW all.)中的总生物碱,考察大孔吸附树脂对大叶钩藤总生物碱的吸附能力。结果筛选出D-101的吸附效果最好,静态吸附容量为112.5m g/m l,动态吸附容量为82.7 m g/m l,选用D-101大孔吸附树脂能很好地提取分离大叶钩藤总生物碱。提取大叶钩藤总生物碱时,用8倍树脂体积的0.08m ol/L盐酸作洗脱剂,成本低、总生物碱洗脱完全,工艺稳定性试验产品含量达36.7%。更多还原

【Abstract】 Choose 6 kinds of macroporous adsorption resins(AB-8,NKA-9,NKA-Ⅱ,DA-201,D-101,D001) extraction and separation the total alkaloid from Uncaria macrophylla Wall.,inspection macroporous adsorption resins adsorptive capacity to total alkaloid of the Uncaria macrophylla Wall.The result showed that D-101 gave good separation performance,the static adsorption capacities were 112.5mg/ml,the stir adsorption capacities were 82.7mg/ml.Selects D-101 to be able to extract and separate the total alkaloid well.When extracts the total alkaloid and uses the 8 time of volumes 0.08mol/L hydrochloric acid to wash,the cost is low,the total alkaloid elutes completely,the content in experimental stability is 36.7%.更多还原