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核素骨显像在71例骨外恶性淋巴瘤的临床应用

The clinical application of nuclide bone imaging in malignant lymphomas

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【作者】 金星唐明灯林端瑜倪雷春

【Author】 JIN Xing, TANG Ming-deng, LIN Duan-yu , NI Lei-chun (Department of Nuclear Medicine, Fujian Tumor Hospital, Fuzhou 350014, China)

【机构】 福建省肿瘤医院核医学科福建省肿瘤医院核医学科

【摘要】 目的探讨核素骨显像在恶性淋巴瘤骨浸润中的临床应用价值。方法收集经病理证实的71例恶性淋巴瘤骨显像患者病例,其中霍奇金淋巴瘤(HL)8例,非霍奇金淋巴瘤(NHL)63例。经静脉注射99mTc-垭甲基二膦酸盐(99mTc-MDP)555-925 MBq后2.5-6h行全身骨显像检查。结果骨浸润病变者31例,其中8例HL中骨浸润3例,63例NHL中骨浸润28例。总病灶数103个,除2个骨放射性缺损外,101个浓聚灶分别为:脊柱35个(34.65%)、四肢骨及关节30个(29.70%)、肋骨14个(13.86%)、骨盆13个(12.87%)、颅骨5个(4.95%)及胸骨4个(3.96%)。结论核素骨显像在恶性淋巴瘤骨浸润的临床分期、治疗监测和预后转归等方面具有较高的临床价值。

【Abstract】 Objective To evaluate the clinical application value of nuclide bone imaging in malignant lymphoma. Methods 71 cases of patients were diagnosed by pathology as malignant lymphoma, among whom there were 8 cases of Hodgkin disease(HL) and 63 cases of non-Hodgkin disease (NHL). The examinations were performed from 2.5 to 6 hours later after the intravenous injection of 99mTc-MDP (555 ~ 925MBq). Results 31 cases were bone-infiltrating lesions, including 3 cases of HL and 28 cases of NHL. The total number of the focus was 103, except 2 cases of bone lack , including 35 foci in vertebral column (34.65%), 30 foci in limb and joint (29.70%), 14 foci in rib (13.86%), 13 foci in elvis (12.9%), 5 foci in skull (4.95%) and 4 foci in sternum (3.96%). Conclusion The nuclide bone imaging has a high value in the clinical stage, therapeutic observation and prognosis of bone-infiltrating malignant lymphoma.

【关键词】 淋巴瘤骨骼99m锝美罗酸盐
【Key words】 LymphomaSkeletonTechnetium 99m medronate
  • 【文献出处】 国际放射医学核医学杂志 ,International Journal of Radiation Medicine and Nuclear Medicine , 编辑部邮箱 ,2006年04期
  • 【分类号】R733.1
  • 【被引频次】1
  • 【下载频次】65
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