节点文献
复合神经营养因子的神经导管研究进展
Progress of nerve guidance channels incorporated neurotrophic factors
【摘要】 目前周围神经的组织工程研究热点之一就是研制具有生物活性的神经导管,主要方法是神经导管与雪旺细胞或者神经营养因子相结合来促进周围神经的再生。就复合神经营养因子的神经导管的相关研究进展作一综述。
【Abstract】 This review discusses several strategies that have been employed to enhance the regenerative effectiveness of artificial nerve guidance channels. These strategies include the use of scaffolds, the integration of contact-mediated cues within the tubular construct, and incorporation or delivery of exogenous growth factors into the conduit lumen uniformly or in a gradient form. Animal and clinical studies are reviewed to explain some of the ideas involved in developing a guidance channel of the future.
【基金】 辽宁省教育厅高等学校科学研究项目(202173365)
- 【文献出处】 国际生物医学工程杂志 ,International Journal of Biomedical Engineering , 编辑部邮箱 ,2006年02期
- 【分类号】R33
- 【被引频次】3
- 【下载频次】219