【摘要】 近年来,有很多流行病学调查证实了HCV感染与糖尿病的关联,这种关联在年龄大、体重超标的患者身上表现更为明显。HCV编码的蛋白,能干扰胰岛素的信号转导,这就解释了在发生肝纤维化之前,HCV感染者出现胰岛素抵抗的原因,而胰岛素抵抗也促进了肝纤维化的进程。更多还原

【Abstract】 Nowadays,several epidemiologic studies have confirmed the link between hepatitis C virus(HCV) infection and diabetes mellitus, which is more obvious in those patients overweight or with an old age. The protein coded by HCV can interrupt signaling of insulin, which accounts for why patients with HCV show insulin resistance before liver cirrhosis.Meanwhile, insulin resistance accelerates the course of cirrhosis.更多还原